Design and manufacture of low cost vaccine cooler

Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2007.

Бібліографічні деталі
Автор: Panas, Cynthia Dawn Walker.
Інші автори: John G. Brisson, II.
Формат: Дисертація
Мова:eng
Опубліковано: Massachusetts Institute of Technology 2008
Предмети:
Онлайн доступ:http://hdl.handle.net/1721.1/40937
_version_ 1826202956640288768
author Panas, Cynthia Dawn Walker.
author2 John G. Brisson, II.
author_facet John G. Brisson, II.
Panas, Cynthia Dawn Walker.
author_sort Panas, Cynthia Dawn Walker.
collection MIT
description Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2007.
first_indexed 2024-09-23T12:28:31Z
format Thesis
id mit-1721.1/40937
institution Massachusetts Institute of Technology
language eng
last_indexed 2024-09-23T12:28:31Z
publishDate 2008
publisher Massachusetts Institute of Technology
record_format dspace
spelling mit-1721.1/409372019-04-12T20:21:45Z Design and manufacture of low cost vaccine cooler Panas, Cynthia Dawn Walker. John G. Brisson, II. Massachusetts Institute of Technology. Dept. of Mechanical Engineering. Massachusetts Institute of Technology. Dept. of Mechanical Engineering. Mechanical Engineering. Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2007. Includes bibliographical references (p. 58). Vaccines are very sensitive to temperature, needing to be held between 2 and 80°C to maintain potency. In developing countries where electricity and fuel supplies are unreliable, many vaccines are ruined due to thermal exposure. These are also the locations where vaccines are needed the most, yet often many of the vaccines given are ineffective. Long holdover vaccine coolers are designed to maintain a proper internal temperature during long periods of power loss. The most prevalent technology is the ice-lined cooler, but in the field these often have problem with freezing the vaccines. A vaccine cooler was designed that modifies the ice-jacket idea by separating the ice compartment and the vaccine chamber, connecting them through a heat transfer regulating device. The objective of this research is to design and prototype the heat transfer regulating device. After several design iterations a cooling loop filled with R-134a made of 1/8 piping, a 0.055 in ID capillary, and a Clippard normally-closed valve was combined with a modified car thermostat, using peanut oil as its working fluid, to create a thermosyphon type heat transfer device with a safety shutoff to prevent freezing. The prototype was manufactured and tested. It was found that with the proper amount of working fluid, it is possible to run the cooling loop at 4°C and pull heat from the vaccine chamber side to the ice. The peanut oil thermostat was tested and was found to open at a slightly lower temperature than expected, 2.5°C, but still within range. These results indicate that the concept is viable and should be tested in the vaccine cooler. by Cynthia D. Walker. S.B. 2008-03-27T18:25:22Z 2008-03-27T18:25:22Z 2007 2007 Thesis http://hdl.handle.net/1721.1/40937 212409598 eng M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/7582 58 p. application/pdf Massachusetts Institute of Technology
spellingShingle Mechanical Engineering.
Panas, Cynthia Dawn Walker.
Design and manufacture of low cost vaccine cooler
title Design and manufacture of low cost vaccine cooler
title_full Design and manufacture of low cost vaccine cooler
title_fullStr Design and manufacture of low cost vaccine cooler
title_full_unstemmed Design and manufacture of low cost vaccine cooler
title_short Design and manufacture of low cost vaccine cooler
title_sort design and manufacture of low cost vaccine cooler
topic Mechanical Engineering.
url http://hdl.handle.net/1721.1/40937
work_keys_str_mv AT panascynthiadawnwalker designandmanufactureoflowcostvaccinecooler