Assessment of ion-selective optical nanosensors for drug screening applications
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2007.
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| Other Authors: | |
| Format: | Thesis |
| Language: | eng |
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Massachusetts Institute of Technology
2008
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| Online Access: | http://hdl.handle.net/1721.1/42129 |
| _version_ | 1826201540354899968 |
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| author | Yun, Hannah |
| author2 | Heather A. Clark. |
| author_facet | Heather A. Clark. Yun, Hannah |
| author_sort | Yun, Hannah |
| collection | MIT |
| description | Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2007. |
| first_indexed | 2024-09-23T11:53:01Z |
| format | Thesis |
| id | mit-1721.1/42129 |
| institution | Massachusetts Institute of Technology |
| language | eng |
| last_indexed | 2024-09-23T11:53:01Z |
| publishDate | 2008 |
| publisher | Massachusetts Institute of Technology |
| record_format | dspace |
| spelling | mit-1721.1/421292019-04-11T02:59:05Z Assessment of ion-selective optical nanosensors for drug screening applications Yun, Hannah Heather A. Clark. Massachusetts Institute of Technology. Dept. of Materials Science and Engineering. Massachusetts Institute of Technology. Dept. of Materials Science and Engineering. Materials Science and Engineering. Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2007. "September 2007." Includes bibliographical references (p. 67-69). Ion channels represent an important category of drug targets. They play a significant role in numerous physiological functions, from membrane excitation and signaling to fluid absorption and secretion. An ion-channel assay system using optical nanosensors has recently been developed. This high-throughput, high-content system improves on the existing patch clamp and fluorescent dye technologies that presently dominate the ion-channel screening market. This paper introduces the nanosensor technology, reviews the current market for ion-channel assays, assesses the costs associated with the nanosensors, and evaluates their commercialization potential. by Hannah Yun. M.Eng. 2008-09-03T14:40:26Z 2008-09-03T14:40:26Z 2007 Thesis http://hdl.handle.net/1721.1/42129 227814259 eng M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/7582 69 p. application/pdf Massachusetts Institute of Technology |
| spellingShingle | Materials Science and Engineering. Yun, Hannah Assessment of ion-selective optical nanosensors for drug screening applications |
| title | Assessment of ion-selective optical nanosensors for drug screening applications |
| title_full | Assessment of ion-selective optical nanosensors for drug screening applications |
| title_fullStr | Assessment of ion-selective optical nanosensors for drug screening applications |
| title_full_unstemmed | Assessment of ion-selective optical nanosensors for drug screening applications |
| title_short | Assessment of ion-selective optical nanosensors for drug screening applications |
| title_sort | assessment of ion selective optical nanosensors for drug screening applications |
| topic | Materials Science and Engineering. |
| url | http://hdl.handle.net/1721.1/42129 |
| work_keys_str_mv | AT yunhannah assessmentofionselectiveopticalnanosensorsfordrugscreeningapplications |