Different gene regulation strategies revealed by analysis of binding motifs

Coordinated regulation of gene expression relies on transcription factors (TFs) binding to specific DNA sites. Our large-scale information-theoretic analysis of >950 TF-binding motifs demonstrates that prokaryotes and eukaryotes use strikingly different strategies to target TFs to specific genom...

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Bibliographic Details
Main Authors: Mirny, Leonid A., Wunderlich, Zeba
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Elsevier Ltd. 2009
Online Access:http://hdl.handle.net/1721.1/49486
https://orcid.org/0000-0002-0785-5410

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