Closing gaps in the human genome using sequencing by synthesis

Closing gaps in the human genome using sequencing by synthesis

The most recent release of the finished human genome contains 260 euchromatic gaps (excluding chromosome Y). Recent work has helped explain a large number of these unresolved regions as 'structural' in nature. Another class of gaps is likely to be refractory to clone-based approaches, and...

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Bibliographic Details
Main Authors: Arachchi, Harindra M., Green, Lisa M., Zody, Michael C., Lennon, Niall, Gnerre, Sante, Berlin, Aaron M., Nusbaum, Chad, Garber, Manuel
Other Authors: Broad Institute of MIT and Harvard
Format: Article
Language:en_US
Published: BioMed Central Ltd. 2009
Online Access:http://hdl.handle.net/1721.1/49494

Internet

http://hdl.handle.net/1721.1/49494

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