Closing gaps in the human genome using sequencing by synthesis
The most recent release of the finished human genome contains 260 euchromatic gaps (excluding chromosome Y). Recent work has helped explain a large number of these unresolved regions as 'structural' in nature. Another class of gaps is likely to be refractory to clone-based approaches, and...
Main Authors: | Arachchi, Harindra M., Green, Lisa M., Zody, Michael C., Lennon, Niall, Gnerre, Sante, Berlin, Aaron M., Nusbaum, Chad, Garber, Manuel |
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Other Authors: | Broad Institute of MIT and Harvard |
Format: | Article |
Language: | en_US |
Published: |
BioMed Central Ltd.
2009
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Online Access: | http://hdl.handle.net/1721.1/49494 |
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