Linking high-resolution metabolic flux phenotypes and transcriptional regulation in yeast modulated by the global regulator Gcn4p

Genome sequencing dramatically increased our ability to understand cellular response to perturbation. Integrating system-wide measurements such as gene expression with networks of protein–protein interactions and transcription factor binding revealed critical insights into cellular behavior. However...

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Bibliographic Details
Main Authors: Moxley, Joel F., Jewett, Michael C., Antoniewicz, Maciek R., Villas-Boas, Silas G., Alper, Hal, Wheeler, Robert T., Tong, Lily V., Hinnebusch, Alan G., Ideker, Trey, Nielsen, Jens Kromann, Stephanopoulos, Gregory
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: National Academy of Sciences 2009
Online Access:http://hdl.handle.net/1721.1/50252
https://orcid.org/0000-0001-6909-4568