Transdermal drug delivery by localized intervention
Both field-confined skin electroporation and microscissioning offer minimally invasive methods for delivering drugs across skin and nail with minimal sensation. Both methods create high permeability pathways in a pain-free manner. These openings are similar in dimension to commonly experienced scrat...
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| Format: | Article |
| Language: | en_US |
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Institute of Electrical and Electronics Engineers
2010
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| Online Access: | http://hdl.handle.net/1721.1/52351 https://orcid.org/0000-0002-9016-5962 |
| _version_ | 1811089858509144064 |
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| author | Weaver, James C. Herndon, Terry O. Gowrishankar, Thiruvallur R. |
| author2 | Harvard University--MIT Division of Health Sciences and Technology |
| author_facet | Harvard University--MIT Division of Health Sciences and Technology Weaver, James C. Herndon, Terry O. Gowrishankar, Thiruvallur R. |
| author_sort | Weaver, James C. |
| collection | MIT |
| description | Both field-confined skin electroporation and microscissioning offer minimally invasive methods for delivering drugs across skin and nail with minimal sensation. Both methods create high permeability pathways in a pain-free manner. These openings are similar in dimension to commonly experienced scratches and nicks on the skin. These localized openings provide pathways for sustained delivery of drugs either passively using a patch or actively using pressure or iontophoresis. |
| first_indexed | 2024-09-23T14:25:48Z |
| format | Article |
| id | mit-1721.1/52351 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T14:25:48Z |
| publishDate | 2010 |
| publisher | Institute of Electrical and Electronics Engineers |
| record_format | dspace |
| spelling | mit-1721.1/523512022-10-01T21:17:53Z Transdermal drug delivery by localized intervention Weaver, James C. Herndon, Terry O. Gowrishankar, Thiruvallur R. Harvard University--MIT Division of Health Sciences and Technology Gowrishankar, Thiruvallur R. Weaver, James C. Herndon, Terry O. Gowrishankar, Thiruvallur R. Both field-confined skin electroporation and microscissioning offer minimally invasive methods for delivering drugs across skin and nail with minimal sensation. Both methods create high permeability pathways in a pain-free manner. These openings are similar in dimension to commonly experienced scratches and nicks on the skin. These localized openings provide pathways for sustained delivery of drugs either passively using a patch or actively using pressure or iontophoresis. IEEE Engineering in Medicine and Biology Society Center for Integration of Medicine and Innovative Technology Massachusetts General Hospital National Institutes of Health (RO1-AR4921 and RO1-GM6387) Lincoln Laboratory 2010-03-05T18:42:01Z 2010-03-05T18:42:01Z 2009-01 Article http://purl.org/eprint/type/JournalArticle 0739-5175 http://hdl.handle.net/1721.1/52351 Gowrishankar, T.R., T.O. Herndon, and J.C. Weaver. “Transdermal drug delivery by localized intervention.” Engineering in Medicine and Biology Magazine, IEEE 28.1 (2009): 55-63. © Copyright 2009 IEEE https://orcid.org/0000-0002-9016-5962 en_US http://dx.doi.org/10.1109/MEMB.2008.931016 IEEE Engineering in Medicine and Biology Magazine Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf Institute of Electrical and Electronics Engineers IEEE |
| spellingShingle | Weaver, James C. Herndon, Terry O. Gowrishankar, Thiruvallur R. Transdermal drug delivery by localized intervention |
| title | Transdermal drug delivery by localized intervention |
| title_full | Transdermal drug delivery by localized intervention |
| title_fullStr | Transdermal drug delivery by localized intervention |
| title_full_unstemmed | Transdermal drug delivery by localized intervention |
| title_short | Transdermal drug delivery by localized intervention |
| title_sort | transdermal drug delivery by localized intervention |
| url | http://hdl.handle.net/1721.1/52351 https://orcid.org/0000-0002-9016-5962 |
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