In Vivo characterization of skin using a weiner nonlinear stochastic identification method

This paper describes an indentometer device used to identify the linear dynamic and nonlinear properties of skin and underlying tissue using an in vivo test. The device uses a Lorentz force actuator to apply a dynamic force to the skin and measures the resulting displacement. It was found that the s...

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Main Authors: Chen, Yi, Hunter, Ian
Other Authors: Massachusetts Institute of Technology. BioInstrumentation Laboratory
Format: Article
Language:en_US
Published: Institute of Electrical and Electronics Engineers 2010
Online Access:http://hdl.handle.net/1721.1/52577
https://orcid.org/0000-0003-2314-3031
https://orcid.org/0000-0002-8251-5432
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author Chen, Yi
Hunter, Ian
author2 Massachusetts Institute of Technology. BioInstrumentation Laboratory
author_facet Massachusetts Institute of Technology. BioInstrumentation Laboratory
Chen, Yi
Hunter, Ian
author_sort Chen, Yi
collection MIT
description This paper describes an indentometer device used to identify the linear dynamic and nonlinear properties of skin and underlying tissue using an in vivo test. The device uses a Lorentz force actuator to apply a dynamic force to the skin and measures the resulting displacement. It was found that the skin could be modeled as a Wiener system (i.e. a linear dynamic system followed by a static nonlinearity). Using a stochastic nonlinear system identification technique, the method presented in this paper was able to identify the dynamic linear and static nonlinear mechanical parameters of the indentometer-skin system within 2 to 4 seconds. The shape of the nonlinearity was found to vary depending on the area of the skin that was tested. We show that the device can repeatably distinguish between different areas of human tissue for multiple test subjects.
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spelling mit-1721.1/525772022-10-01T09:10:03Z In Vivo characterization of skin using a weiner nonlinear stochastic identification method Chen, Yi Hunter, Ian Massachusetts Institute of Technology. BioInstrumentation Laboratory Koch Institute for Integrative Cancer Research at MIT Hunter, Ian Chen, Yi Hunter, Ian This paper describes an indentometer device used to identify the linear dynamic and nonlinear properties of skin and underlying tissue using an in vivo test. The device uses a Lorentz force actuator to apply a dynamic force to the skin and measures the resulting displacement. It was found that the skin could be modeled as a Wiener system (i.e. a linear dynamic system followed by a static nonlinearity). Using a stochastic nonlinear system identification technique, the method presented in this paper was able to identify the dynamic linear and static nonlinear mechanical parameters of the indentometer-skin system within 2 to 4 seconds. The shape of the nonlinearity was found to vary depending on the area of the skin that was tested. We show that the device can repeatably distinguish between different areas of human tissue for multiple test subjects. 2010-03-15T16:05:33Z 2010-03-15T16:05:33Z 2009-11 2009-04 Article http://purl.org/eprint/type/ConferencePaper 978-1-4244-3296-7 1557-170X http://hdl.handle.net/1721.1/52577 Yi Chen, and I.W. Hunter. “In Vivo characterization of skin using a weiner nonlinear stochastic system identification method.” Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE. 2009. 6010-6013. © 2009 IEEE https://orcid.org/0000-0003-2314-3031 https://orcid.org/0000-0002-8251-5432 en_US http://dx.doi.org/10.1109/IEMBS.2009.5334028 2009 Engineering in Medicine and Biology Society Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf Institute of Electrical and Electronics Engineers IEEE
spellingShingle Chen, Yi
Hunter, Ian
In Vivo characterization of skin using a weiner nonlinear stochastic identification method
title In Vivo characterization of skin using a weiner nonlinear stochastic identification method
title_full In Vivo characterization of skin using a weiner nonlinear stochastic identification method
title_fullStr In Vivo characterization of skin using a weiner nonlinear stochastic identification method
title_full_unstemmed In Vivo characterization of skin using a weiner nonlinear stochastic identification method
title_short In Vivo characterization of skin using a weiner nonlinear stochastic identification method
title_sort in vivo characterization of skin using a weiner nonlinear stochastic identification method
url http://hdl.handle.net/1721.1/52577
https://orcid.org/0000-0003-2314-3031
https://orcid.org/0000-0002-8251-5432
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