Cytoplasmic Relaxation of Active Eph Controls Ephrin Shedding by ADAM10

Cytoplasmic Relaxation of Active Eph Controls Ephrin Shedding by ADAM10

Release of cell surface-bound ligands by A-Disintegrin-And-Metalloprotease (ADAM) transmembrane metalloproteases is essential for signalling by cytokine, cell adhesion, and tyrosine kinase receptors. For Eph receptor ligands, it provides the switch between cell-cell adhesion and repulsion. Ligand sh...

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Bibliographic Details
Main Authors: Janes, Peter W., Wimmer-Kleikamp, Sabine H., Frangakis, Achilleas S., Treble, Kane, Griensshaber, Bettina, Sabet, Ola, Grabenbauer, Markus, Ting, Alice Y., Saftig, Paul, Bastiaens, Philippe I., Lackmann, Martin
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: Public Library of Science 2010
Online Access:http://hdl.handle.net/1721.1/52586
https://orcid.org/0000-0002-8277-5226

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