Loss of PDZK1 Causes Coronary Artery Occlusion and Myocardial Infarction in Paigen Diet-Fed Apolipoprotein E Deficient Mice

Background: PDZK1 is a four PDZ-domain containing protein that binds to the carboxy terminus of the HDL receptor, scavenger receptor class B type I (SR-BI), and regulates its expression, localization and function in a tissue-specific manner. PDZK1 knockout (KO) mice are characterized by a marked red...

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Bibliographic Details
Main Authors: Krieger, Monty, Yesilaltay, Ayce, Kocher, Olivier, Pal, Rinku, Daniels, Kathleen
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Public Library of Science 2010
Online Access:http://hdl.handle.net/1721.1/54714
https://orcid.org/0000-0003-4541-5181
https://orcid.org/0000-0001-9905-5316