A Microsaccadic Rhythm Modulates Gamma-Band Synchronization and Behavior
Rhythms occur both in neuronal activity and in behavior. Behavioral rhythms abound at frequencies at or below 10 Hz. Neuronal rhythms cover a very wide frequency range, and the phase of neuronal low-frequency rhythms often rhythmically modulates the strength of higher-frequency rhythms, particul...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
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Society for Neuroscience
2010
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| Online Access: | http://hdl.handle.net/1721.1/55391 https://orcid.org/0000-0002-5938-4227 |
| _version_ | 1811080646847627264 |
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| author | Fries, Pascal Womelsdorf, Thilo Bosman, Conrado A. Desimone, Robert |
| author2 | McGovern Institute for Brain Research at MIT |
| author_facet | McGovern Institute for Brain Research at MIT Fries, Pascal Womelsdorf, Thilo Bosman, Conrado A. Desimone, Robert |
| author_sort | Fries, Pascal |
| collection | MIT |
| description | Rhythms occur both in neuronal activity and in behavior. Behavioral rhythms abound at frequencies at or below 10 Hz. Neuronal rhythms cover a very wide frequency range, and the phase of neuronal low-frequency rhythms often rhythmically modulates the strength of higher-frequency rhythms, particularly of gamma-band synchronization (GBS). Here, we study stimulus-induced GBS in awake monkey areas V1 and V4 in relation to a specific form of spontaneous behavior, namely microsaccades (MSs), small fixational eye movements. We found that MSs occur rhythmically at a frequency of ~3.3 Hz. The rhythmic MSs were predicted by the phase of the 3.3 Hz rhythm in V1 and V4 local field potentials. In turn, the MSs modulated both visually induced GBS and the speed of visually triggered behavioral responses. Fast/slow responses were preceded by a specific temporal pattern of MSs. These MS patterns induced perturbations in GBS that in turn explained variability in behavioral response speed. We hypothesize that the 3.3 Hz rhythm structures the sampling and exploration of the environment through building and breaking neuronal ensembles synchronized in the gamma-frequency band to process sensory stimuli. |
| first_indexed | 2024-09-23T11:34:36Z |
| format | Article |
| id | mit-1721.1/55391 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T11:34:36Z |
| publishDate | 2010 |
| publisher | Society for Neuroscience |
| record_format | dspace |
| spelling | mit-1721.1/553912022-09-27T20:28:09Z A Microsaccadic Rhythm Modulates Gamma-Band Synchronization and Behavior Fries, Pascal Womelsdorf, Thilo Bosman, Conrado A. Desimone, Robert McGovern Institute for Brain Research at MIT Desimone, Robert Desimone, Robert Rhythms occur both in neuronal activity and in behavior. Behavioral rhythms abound at frequencies at or below 10 Hz. Neuronal rhythms cover a very wide frequency range, and the phase of neuronal low-frequency rhythms often rhythmically modulates the strength of higher-frequency rhythms, particularly of gamma-band synchronization (GBS). Here, we study stimulus-induced GBS in awake monkey areas V1 and V4 in relation to a specific form of spontaneous behavior, namely microsaccades (MSs), small fixational eye movements. We found that MSs occur rhythmically at a frequency of ~3.3 Hz. The rhythmic MSs were predicted by the phase of the 3.3 Hz rhythm in V1 and V4 local field potentials. In turn, the MSs modulated both visually induced GBS and the speed of visually triggered behavioral responses. Fast/slow responses were preceded by a specific temporal pattern of MSs. These MS patterns induced perturbations in GBS that in turn explained variability in behavioral response speed. We hypothesize that the 3.3 Hz rhythm structures the sampling and exploration of the environment through building and breaking neuronal ensembles synchronized in the gamma-frequency band to process sensory stimuli. 7th European Community Framework Programme (FP7/2007-2013) Beca Presidente de la República, Gobierno de Chile (C.A.B.) 2010-06-03T20:21:06Z 2010-06-03T20:21:06Z 2009-06 2009-05 Article http://purl.org/eprint/type/JournalArticle 0270-6474 http://hdl.handle.net/1721.1/55391 Bosman, Conrado A., Thilo Womelsdorf, Robert Desimone, and Pascal Fries. "A Microsaccadic Rhythm Modulates Gamma-Band Synchronization and Behavior." J. Neurosci., Jul 2009; 29: 9471 - 9480. © 2009 Society of Neuroscience. https://orcid.org/0000-0002-5938-4227 en_US http://dx.doi.org/10.1523/jneurosci.1193-09.2009 Journal of Neuroscience Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf Society for Neuroscience Society for Neuroscience |
| spellingShingle | Fries, Pascal Womelsdorf, Thilo Bosman, Conrado A. Desimone, Robert A Microsaccadic Rhythm Modulates Gamma-Band Synchronization and Behavior |
| title | A Microsaccadic Rhythm Modulates Gamma-Band Synchronization and Behavior |
| title_full | A Microsaccadic Rhythm Modulates Gamma-Band Synchronization and Behavior |
| title_fullStr | A Microsaccadic Rhythm Modulates Gamma-Band Synchronization and Behavior |
| title_full_unstemmed | A Microsaccadic Rhythm Modulates Gamma-Band Synchronization and Behavior |
| title_short | A Microsaccadic Rhythm Modulates Gamma-Band Synchronization and Behavior |
| title_sort | microsaccadic rhythm modulates gamma band synchronization and behavior |
| url | http://hdl.handle.net/1721.1/55391 https://orcid.org/0000-0002-5938-4227 |
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