| Summary: | There are many reports showing that low-level light/laser therapy (LLLT) can enhance wound healing,
upregulate cell proliferation and has anti-apoptotic effects by activating intracellular protective genes. In
the field of immune response study, it is not known with any certainty whether light/laser is proinflammatory
or anti-inflammatory. Increasingly in recent times dendritic cells have been found to play
an important role in inflammation and the immunological response. In this study, we try to look at the
impact of low level near infrared light (810-nm) on murine bone-marrow derived dendritic cells. Changes
in surface markers, including MHC II, CD80 and CD11c and the secretion of interleukins induced by light
may provide additional evidence to reveal the mystery of how light affects the maturation of dendritic
cells as well how these light-induced mature dendritic cells would affect the activation of adaptive
immune response.
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