A quantitative model of transcriptional regulation reveals the influence binding location on expression
Understanding the mechanistic basis of transcriptional regulation has been a central focus of molecular biology since its inception. New high-throughput chromatin immunoprecipitation experiments have revealed that most regulatory proteins bind thousands of sites in mammalian genomes. However, the fu...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Public Library of Science
2010
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| Online Access: | http://hdl.handle.net/1721.1/57501 https://orcid.org/0000-0001-9249-8181 |