A quantitative model of transcriptional regulation reveals the influence binding location on expression

Understanding the mechanistic basis of transcriptional regulation has been a central focus of molecular biology since its inception. New high-throughput chromatin immunoprecipitation experiments have revealed that most regulatory proteins bind thousands of sites in mammalian genomes. However, the fu...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän: MacIsaac, Kenzie Daniel, Lo, Kinyui Alice, Gordon, William, Motola, Shmulik, Mazor, Tali, Fraenkel, Ernest
Övriga upphovsmän: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Materialtyp: Artikel
Språk:en_US
Publicerad: Public Library of Science 2010
Länkar:http://hdl.handle.net/1721.1/57501
https://orcid.org/0000-0001-9249-8181

Liknande verk