Microwell-mediated Control of Embryoid Body Size Regulates Embryonic Stem Cell Fate Via Differential Expression of WNT5a and WNT11

Microwell-mediated Control of Embryoid Body Size Regulates Embryonic Stem Cell Fate Via Differential Expression of WNT5a and WNT11

Recently, various approaches for controlling the embryonic stem (ES) cell microenvironment have been developed for regulating cellular fate decisions. It has been reported that the lineage specific differentiation could be affected by the size of ES cell colonies and embryoid bodies (EBs). However,...

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Bibliographic Details
Main Authors: Khademhosseini, Ali, Hwang, Yu-Shik, Chung, Bong Geun, Moeller, Hannes-Christian, Ortmann, Daniel, Hattori, Nobuaki
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2010
Subjects:
Hydrogel microwells
Stem cell differentiation
WNT signal pathway
Online Access:http://hdl.handle.net/1721.1/58302

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