A wireless-compatible CMOS-based celluar sensor
The title as published reads "celluar sensor" but should be "cellular sensor."
| Main Authors: | , |
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| Format: | Article |
| Language: | en_US |
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Institute of Electrical and Electronics Engineers
2010
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| Online Access: | http://hdl.handle.net/1721.1/58840 |
| _version_ | 1826192020752826368 |
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| author | Matsudaira, Paul T. Anwar, Mekhail |
| author2 | Massachusetts Institute of Technology. Department of Biological Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Biological Engineering Matsudaira, Paul T. Anwar, Mekhail |
| author_sort | Matsudaira, Paul T. |
| collection | MIT |
| description | The title as published reads "celluar sensor" but should be "cellular sensor." |
| first_indexed | 2024-09-23T09:05:03Z |
| format | Article |
| id | mit-1721.1/58840 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T09:05:03Z |
| publishDate | 2010 |
| publisher | Institute of Electrical and Electronics Engineers |
| record_format | dspace |
| spelling | mit-1721.1/588402022-09-30T13:19:19Z A wireless-compatible CMOS-based celluar sensor Matsudaira, Paul T. Anwar, Mekhail Massachusetts Institute of Technology. Department of Biological Engineering Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Whitehead Institute for Biomedical Research Matsudaira, Paul T. Matsudaira, Paul T. Anwar, Mekhail CMOS Imaging Array Cell-based Biosensor Luciferase The title as published reads "celluar sensor" but should be "cellular sensor." Biosensors have a need to accurately detect and quantify a biological target within a complex medium, such as serum. Cells are uniquely qualified to accomplish this, but cannot communicate with the outside world. We demonstrate a synergistic fusion between a genetically engineered cell line and a wireless-compatible CMOS sensor leveraging the cells innate ability to specifically bind, amplify and transduce the signal with electronics that are capable transforming this cellular signal into an electronic one. We demonstrate the detection of TNF-alpha (TNFalpha) within serum without washing. Since cells are real-time transducers of binding events, real-time monitoring of biological agents and reactions are possible. 2010-10-01T20:15:02Z 2010-10-01T20:15:02Z 2009-06 Article http://purl.org/eprint/type/JournalArticle 978-1-4244-4190-7 INSPEC Accession Number: 10916883 E-ISBN: 978-1-4244-4193-8 http://hdl.handle.net/1721.1/58840 M. Anwar and P. Matsudaira, “Wireless-compatible CMOS-based celluar sensor,” in Solid-State Sensors, Actuators and Microsystems Conference, 2009. TRANSDUCERS 2009. International, 2009, 936-938, 10.1109/SENSOR.© 2009, IEEE en_US http://dx.doi.org/10.1109/SENSOR.2009.5285970 Solid-State Sensors, Actuators and Microsystems Conference. TRANSDUCERS Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf Institute of Electrical and Electronics Engineers IEEE |
| spellingShingle | CMOS Imaging Array Cell-based Biosensor Luciferase Matsudaira, Paul T. Anwar, Mekhail A wireless-compatible CMOS-based celluar sensor |
| title | A wireless-compatible CMOS-based celluar sensor |
| title_full | A wireless-compatible CMOS-based celluar sensor |
| title_fullStr | A wireless-compatible CMOS-based celluar sensor |
| title_full_unstemmed | A wireless-compatible CMOS-based celluar sensor |
| title_short | A wireless-compatible CMOS-based celluar sensor |
| title_sort | wireless compatible cmos based celluar sensor |
| topic | CMOS Imaging Array Cell-based Biosensor Luciferase |
| url | http://hdl.handle.net/1721.1/58840 |
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