Altering coenzyme specificity of Pichia stipitis xylose reductase by the semi-rational approach CASTing
Background: The NAD(P)H-dependent Pichia stipitis xylose reductase (PsXR) is one of the key enzymes for xylose fermentation, and has been cloned into the commonly used ethanol-producing yeast Saccharomyces cerevisiae. In order to eliminate the redox imbalance resulting from the preference of this en...
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Format: | Article |
Language: | English |
Published: |
BioMed Central Ltd
2010
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Online Access: | http://hdl.handle.net/1721.1/58912 |