Validation and refinement of gene-regulatory pathways on a network of physical interactions

As genome-scale measurements lead to increasingly complex models of gene regulation, systematic approaches are needed to validate and refine these models. Towards this goal, we describe an automated procedure for prioritizing genetic perturbations in order to discriminate optimally between alternati...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Yeang, Chen-Hsiang, 1969-, Mak, Craig, McCuine, Scott, Workman, Christopher, Ideker, Trey, Jaakkola, Tommi S.
Muut tekijät: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: BioMed Central Ltd 2010
Linkit:http://hdl.handle.net/1721.1/58915
https://orcid.org/0000-0002-2199-0379