Validation and refinement of gene-regulatory pathways on a network of physical interactions

As genome-scale measurements lead to increasingly complex models of gene regulation, systematic approaches are needed to validate and refine these models. Towards this goal, we describe an automated procedure for prioritizing genetic perturbations in order to discriminate optimally between alternati...

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Bibliographic Details
Main Authors: Yeang, Chen-Hsiang, 1969-, Mak, Craig, McCuine, Scott, Workman, Christopher, Ideker, Trey, Jaakkola, Tommi S.
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:English
Published: BioMed Central Ltd 2010
Online Access:http://hdl.handle.net/1721.1/58915
https://orcid.org/0000-0002-2199-0379

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