Genomic patterns of pathogen evolution revealed by comparison of Burkholderia pseudomallei, the causative agent of melioidosis, to avirulent Burkholderia thailandensis

Genomic patterns of pathogen evolution revealed by comparison of Burkholderia pseudomallei, the causative agent of melioidosis, to avirulent Burkholderia thailandensis

Background: The Gram-negative bacterium Burkholderia pseudomallei (Bp) is the causative agent of the human disease melioidosis. To understand the evolutionary mechanisms contributing to Bp virulence, we performed a comparative genomic analysis of Bp K96243 and B. thailandensis (Bt) E264, a closely r...

Full description

Bibliographic Details
Main Authors: Yu, Yiting, Chua, Hui Hoon, Lin, Chi Ho, Sim, Siew Hoon, Lin, Daoxun, Derr, Alan, Engels, Reinhard, DeShazer, David, Birren, Bruce W., Nierman, William C., Tan, Patrick, Kim, H. Stanley
Other Authors: Broad Institute of MIT and Harvard
Format: Article
Language:English
Published: BioMed Central Ltd 2010
Online Access:http://hdl.handle.net/1721.1/58919

Internet

http://hdl.handle.net/1721.1/58919

Similar Items