Optical techniques for detecting and identifying biological-warfare agents

Rapid and accurate detection and identification of biological agents is an objective of various national security programs. Detection in general is difficult owing to natural clutter and anticipated low concentrations of subject material. Typical detection architectures comprise a nonspecific trigge...

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Main Authors: Greenwood, Darryl P., Jeys, Thomas H., Johnson, Bernadette, Richardson, Jonathan M., Shatz, Michael P.
Other Authors: Lincoln Laboratory
Format: Article
Language:en_US
Published: Institute of Electrical and Electronics Engineers 2010
Online Access:http://hdl.handle.net/1721.1/59348
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author Greenwood, Darryl P.
Jeys, Thomas H.
Johnson, Bernadette
Richardson, Jonathan M.
Shatz, Michael P.
author2 Lincoln Laboratory
author_facet Lincoln Laboratory
Greenwood, Darryl P.
Jeys, Thomas H.
Johnson, Bernadette
Richardson, Jonathan M.
Shatz, Michael P.
author_sort Greenwood, Darryl P.
collection MIT
description Rapid and accurate detection and identification of biological agents is an objective of various national security programs. Detection in general is difficult owing to natural clutter and anticipated low concentrations of subject material. Typical detection architectures comprise a nonspecific trigger, a rapid identifier, and a confirming step, often in a laboratory. High-confidence identification must be made prior to taking action, though this must be traded against regrets stemming from delay. Sensing requirements are best established by positing plausible scenarios, two of which are suggested herein. Modern technologies include the use of elastic scatter and ultraviolet laser-induced fluorescence for triggering and standoff detection. Optical and nonoptical techniques are used routinely in analyzing clinical samples used to confirm infection and illness resulting from a biological attack. Today, environmental sensing serves at best as an alert to medical authorities for possible action, which would include sample collection and detailed analysis. This paper surveys the state of the art of sensing at all levels.
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spelling mit-1721.1/593482022-09-27T22:04:13Z Optical techniques for detecting and identifying biological-warfare agents Greenwood, Darryl P. Jeys, Thomas H. Johnson, Bernadette Richardson, Jonathan M. Shatz, Michael P. Lincoln Laboratory Greenwood, Darryl P. Greenwood, Darryl P. Jeys, Thomas H. Johnson, Bernadette Richardson, Jonathan M. Shatz, Michael P. Rapid and accurate detection and identification of biological agents is an objective of various national security programs. Detection in general is difficult owing to natural clutter and anticipated low concentrations of subject material. Typical detection architectures comprise a nonspecific trigger, a rapid identifier, and a confirming step, often in a laboratory. High-confidence identification must be made prior to taking action, though this must be traded against regrets stemming from delay. Sensing requirements are best established by positing plausible scenarios, two of which are suggested herein. Modern technologies include the use of elastic scatter and ultraviolet laser-induced fluorescence for triggering and standoff detection. Optical and nonoptical techniques are used routinely in analyzing clinical samples used to confirm infection and illness resulting from a biological attack. Today, environmental sensing serves at best as an alert to medical authorities for possible action, which would include sample collection and detailed analysis. This paper surveys the state of the art of sensing at all levels. United States. Dept. of the Air Force (Contract FA8721-05-C-0002) United States. Defense Threat Reduction Agency United States. Dept. of Homeland Security 2010-10-14T20:32:27Z 2010-10-14T20:32:27Z 2009-05 Article http://purl.org/eprint/type/JournalArticle 0018-9219 INSPEC Accession Number: 10664131 http://hdl.handle.net/1721.1/59348 Greenwood, D.P. et al. “Optical Techniques for Detecting and Identifying Biological-Warfare Agents.” Proceedings of the IEEE 97.6 (2009): 971-989. © 2009 IEEE en_US http://dx.doi.org/10.1109/JPROC.2009.2013564 Proceedings of the IEEE Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf Institute of Electrical and Electronics Engineers IEEE
spellingShingle Greenwood, Darryl P.
Jeys, Thomas H.
Johnson, Bernadette
Richardson, Jonathan M.
Shatz, Michael P.
Optical techniques for detecting and identifying biological-warfare agents
title Optical techniques for detecting and identifying biological-warfare agents
title_full Optical techniques for detecting and identifying biological-warfare agents
title_fullStr Optical techniques for detecting and identifying biological-warfare agents
title_full_unstemmed Optical techniques for detecting and identifying biological-warfare agents
title_short Optical techniques for detecting and identifying biological-warfare agents
title_sort optical techniques for detecting and identifying biological warfare agents
url http://hdl.handle.net/1721.1/59348
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