Spatiotemporal controlled delivery of nanoparticles to injured vasculature
There are a number of challenges associated with designing nanoparticles for medical applications. We define two challenges here: (i) conventional targeting against up-regulated cell surface antigens is limited by heterogeneity in expression, and (ii) previous studies suggest that the optimal size o...
Main Authors: | Chan, Juliana Maria, Zhang, Liangfang, Tong, Rong, Ghosh, Debadyuti, Gao, Weiwei, Liao, Grace V., Yuet, Kai P., Gray, David, Rhee, June-Wha, Cheng, Jianjun, Golomb, Gershon, Libby, Peter, Langer, Robert, Farokhzad, Omid C. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences
2011
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Online Access: | http://hdl.handle.net/1721.1/60889 https://orcid.org/0000-0002-1381-8923 https://orcid.org/0000-0003-4255-0492 |
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