Spatiotemporal controlled delivery of nanoparticles to injured vasculature

Spatiotemporal controlled delivery of nanoparticles to injured vasculature

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There are a number of challenges associated with designing nanoparticles for medical applications. We define two challenges here: (i) conventional targeting against up-regulated cell surface antigens is limited by heterogeneity in expression, and (ii) previous studies suggest that the optimal size o...

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Bibliographic Details
Main Authors: Chan, Juliana Maria, Zhang, Liangfang, Tong, Rong, Ghosh, Debadyuti, Gao, Weiwei, Liao, Grace V., Yuet, Kai P., Gray, David, Rhee, June-Wha, Cheng, Jianjun, Golomb, Gershon, Libby, Peter, Langer, Robert, Farokhzad, Omid C.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: National Academy of Sciences 2011
Online Access:http://hdl.handle.net/1721.1/60889
https://orcid.org/0000-0002-1381-8923
https://orcid.org/0000-0003-4255-0492
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