αvβ3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration
Integrins are fundamental to the control of protrusion and motility in adherent cells. However, the mechanisms by which specific members of this receptor family cooperate in signaling to cytoskeletal and adhesion dynamics are poorly understood. Here, we show that the loss of β3 [beta 3] integrin in...
Huvudupphovsmän: | Gertler, Frank, Worth, Daniel C., Hodivala-Dilke, Kairbaan, Robinson, Stephen D., King, Samantha J., Morton, Penny E., Humphries, Martin J., Parsons, Maddy |
---|---|
Övriga upphovsmän: | Massachusetts Institute of Technology. Department of Biology |
Materialtyp: | Artikel |
Språk: | en_US |
Publicerad: |
Rockefeller University Press
2011
|
Länkar: | http://hdl.handle.net/1721.1/60934 https://orcid.org/0000-0003-3214-4554 |
Liknande verk
Liknande verk
-
RIAM, an Ena/VASP and Profilin Ligand, Interacts with Rap1-GTP and Mediates Rap1-Induced Adhesion
av: Lafuente, Esther M., et al.
Publicerad: (2014) -
Mena binds α5 integrin directly and modulates α5β1 function
av: Gupton, Stephanie L., et al.
Publicerad: (2012) -
Selective imaging of the angiogenic relevant integrins α5β1 and αvβ3.
av: Neubauer, S, et al.
Publicerad: (2013) -
Structural and functional characterization of integrin αLβ2
av: Tang, Xiaoyan
Publicerad: (2011) -
Multiple roles of integrin-α3 at the neuromuscular junction.
av: Ross, J, et al.
Publicerad: (2017)