The Crystal Structure of a Junction Between Two Z-DNA Helices

The Crystal Structure of a Junction Between Two Z-DNA Helices

The double helix of DNA, when composed of dinucleotide purine-pyrimidine repeats, can adopt a left-handed helical structure called Z-DNA. For reasons not entirely understood, such dinucleotide repeats in genomic sequences have been associated with genomic instability leading to cancer. Adoption of t...

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Bibliographic Details
Main Authors: Rich, Alexander, de Rosa, Matteo, de Sanctis, Daniele, Rosario, Ana Lucia, Archer, Margarida, Athanasiadis, Alekos, Carrondo, Maria Armenia
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: National Academy of Sciences 2011
Online Access:http://hdl.handle.net/1721.1/61392

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