Revealing strengths and weaknesses of methods for gene network inference

Numerous methods have been developed for inferring gene regulatory networks from expression data, however, both their absolute and comparative performance remain poorly understood. In this paper, we introduce a framework for critical performance assessment of methods for gene network inference. We p...

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Bibliographic Details
Main Authors: Marbach, Daniel, Schaffter, Thomas, Prill, Robert J., Mattiussi, Claudio, Floreano, Dario, Stolovitzky, Gustavo
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: National Academy of Sciences 2011
Online Access:http://hdl.handle.net/1721.1/61406