Caldag-Gefi Down-Regulation in the Striatum as a Neuroprotective Change in Huntington's Disease.

Caldag-Gefi Down-Regulation in the Striatum as a Neuroprotective Change in Huntington's Disease.

Huntingtin protein (Htt) is ubiquitously expressed, yet Huntington’s disease (HD), a fatal neurologic disorder produced by expansion of an Htt polyglutamine tract, is characterized by neurodegeneration that occurs primarily in the striatum and cerebral cortex. Such discrepancies between sites of...

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Bibliographic Details
Main Authors: Dunn, Denise E., Merali, Farhan I., Woodman, Ben, Yim, Michael, Borkowska, Anna E., Frosch, Matthew P., Bates, Gillian P., Lo, Donald C., Crittenden, Jill R, Housman, David E, Graybiel, Ann M
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: IRL Press at Oxford University Press 2011
Online Access:http://hdl.handle.net/1721.1/64695
https://orcid.org/0000-0001-5016-0756
https://orcid.org/0000-0002-4326-7720

Internet

http://hdl.handle.net/1721.1/64695
https://orcid.org/0000-0001-5016-0756
https://orcid.org/0000-0002-4326-7720

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