The Cooperation between hMena Overexpression and HER2 Signalling in Breast Cancer

hMena and the epithelial specific isoform hMena11a are actin cytoskeleton regulatory proteins belonging to the Ena/VASP family. EGF treatment of breast cancer cell lines upregulates hMena/hMena11a expression and phosphorylates hMena11a, suggesting cross-talk between the ErbB receptor family and hMen...

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Bibliographic Details
Main Authors: Di Modugno, Francesca, Mottolese, Marcella, DeMonte, Lucia, Trono, Paola, Terrenato, Irene, Belleudi, Francesca, Torrisi, Maria Rosaria, Alessio, Massimo, Santoni, Angela, Nistico, Paola
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:en_US
Published: Public Library of Science 2011
Online Access:http://hdl.handle.net/1721.1/64748

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