Levodopa-Induced Dyskinesia Is Associated with Increased Thyrotropin Releasing Hormone in the Dorsal Striatum of Hemi-Parkinsonian Rats

Background Dyskinesias associated with involuntary movements and painful muscle contractions are a common and severe complication of standard levodopa (L-DOPA, L-3,4-dihydroxyphenylalanine) therapy for Parkinson's disease. Pathologic neuroplasticity leading to hyper-responsive dopamine recep...

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Bibliographic Details
Main Authors: Cantuti-Castelvetri, Ippolita, Keller-McGandy, Christine E., Kett, Lauren R., Landy, Alex, Hollingsworth, Zane R., Saka, Esen, Crittenden, Jill R., Nillni, Eduardo A., Young, Anne B., Standaert, David G., Graybiel, Ann M., F. Hernandez, Ledia
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: Public Library of Science 2011
Online Access:http://hdl.handle.net/1721.1/64751
https://orcid.org/0000-0003-2381-0834
https://orcid.org/0000-0002-4326-7720