Autocrine-controlled formation and function of tissue-like aggregates by hepatocytes in micropatterned hydrogel arrays
The liver carries out a variety of essential functions regulated in part by autocrine signaling, including hepatocyte-produced growth factors and extracellular matrix (ECM). The local concentrations of autocrine factors are governed by a balance between receptor-mediated binding at the cell surface...
Main Authors: | Williams, Courtney M., Mehta, Geeta, Peyton, Shelly R., Zeiger, Adam Scott, Van Vliet, Krystyn J., Griffith, Linda G. |
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Other Authors: | Massachusetts Institute of Technology. Center for Gynepathology Research |
Format: | Article |
Language: | en_US |
Published: |
Mary Ann Liebert, Inc.
2011
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Online Access: | http://hdl.handle.net/1721.1/64804 https://orcid.org/0000-0001-5735-0560 https://orcid.org/0000-0002-1801-5548 |
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