Perturbing the folding energy landscape of the bacterial immunity protein Im7 by site-specific N-linked glycosylation
N-linked glycosylation modulates protein folding and stability through a variety of mechanisms. As such there is considerable interest in the development of general rules to predict the structural consequences of site-specific glycosylation and to understand how these effects can be exploited in the...
Main Authors: | Chen, Mark, Bartlett, Alice I., Nerenberg, Paul S., Friel, Claire T., Hackenberger, Christian P. R., Radford, Sheena E., Imperiali, Barbara, Stultz, Collin M |
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Other Authors: | Harvard University--MIT Division of Health Sciences and Technology |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences
2011
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Online Access: | http://hdl.handle.net/1721.1/64814 https://orcid.org/0000-0002-3415-242X https://orcid.org/0000-0002-5749-7869 |
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