Sensitivity of MEG and EEG to Source Orientation
An important difference between magnetoencephalography (MEG) and electroencephalography (EEG) is that MEG is insensitive to radially oriented sources. We quantified computationally the dependency of MEG and EEG on the source orientation using a forward model with realistic tissue boundaries. Si...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
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Springer
2011
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| Online Access: | http://hdl.handle.net/1721.1/64950 https://orcid.org/0000-0001-6841-112X |
| _version_ | 1826211066391035904 |
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| author | Ahlfors, Seppo Pentti Han, Jooman Belliveau, John W. Hamalainen, Matti S. |
| author2 | Harvard University--MIT Division of Health Sciences and Technology |
| author_facet | Harvard University--MIT Division of Health Sciences and Technology Ahlfors, Seppo Pentti Han, Jooman Belliveau, John W. Hamalainen, Matti S. |
| author_sort | Ahlfors, Seppo Pentti |
| collection | MIT |
| description | An important difference between magnetoencephalography
(MEG) and electroencephalography (EEG)
is that MEG is insensitive to radially oriented sources. We
quantified computationally the dependency of MEG and
EEG on the source orientation using a forward model with
realistic tissue boundaries. Similar to the simpler case of a
spherical head model, in which MEG cannot see radial
sources at all, for most cortical locations there was a source
orientation to which MEG was insensitive. The median
value for the ratio of the signal magnitude for the source
orientation of the lowest and the highest sensitivity was
0.06 for MEG and 0.63 for EEG. The difference in the
sensitivity to the source orientation is expected to contribute
to systematic differences in the signal-to-noise ratio
between MEG and EEG. |
| first_indexed | 2024-09-23T15:00:21Z |
| format | Article |
| id | mit-1721.1/64950 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T15:00:21Z |
| publishDate | 2011 |
| publisher | Springer |
| record_format | dspace |
| spelling | mit-1721.1/649502022-10-01T23:52:58Z Sensitivity of MEG and EEG to Source Orientation Ahlfors, Seppo Pentti Han, Jooman Belliveau, John W. Hamalainen, Matti S. Harvard University--MIT Division of Health Sciences and Technology Ahlfors, Seppo Pentti Ahlfors, Seppo Pentti Belliveau, John W. Hamalainen, Matti S. An important difference between magnetoencephalography (MEG) and electroencephalography (EEG) is that MEG is insensitive to radially oriented sources. We quantified computationally the dependency of MEG and EEG on the source orientation using a forward model with realistic tissue boundaries. Similar to the simpler case of a spherical head model, in which MEG cannot see radial sources at all, for most cortical locations there was a source orientation to which MEG was insensitive. The median value for the ratio of the signal magnitude for the source orientation of the lowest and the highest sensitivity was 0.06 for MEG and 0.63 for EEG. The difference in the sensitivity to the source orientation is expected to contribute to systematic differences in the signal-to-noise ratio between MEG and EEG. National Institutes of Health (U.S.) (Grant NS057500) National Institutes of Health (U.S.) (Grant NS037462) National Institutes of Health (U.S.) (Grant HD040712) National Center for Research Resources (U.S.) (P41RR14075) Mind Research Network 2011-07-22T16:50:11Z 2011-07-22T16:50:11Z 2010-07 2010-05 Article http://purl.org/eprint/type/JournalArticle 0896-0267 http://hdl.handle.net/1721.1/64950 Ahlfors, Seppo P. et al. “Sensitivity of MEG and EEG to Source Orientation.” Brain Topography 23.3 (2010) : 227-232. Copyright © 2010, The Author(s) https://orcid.org/0000-0001-6841-112X en_US http://dx.doi.org/10.1007/s10548-010-0154-x Brain Topography Creative Commons Attribution Noncommercial License http://creativecommons.org/licenses/by-nc/2.5 application/pdf Springer Springer |
| spellingShingle | Ahlfors, Seppo Pentti Han, Jooman Belliveau, John W. Hamalainen, Matti S. Sensitivity of MEG and EEG to Source Orientation |
| title | Sensitivity of MEG and EEG to Source Orientation |
| title_full | Sensitivity of MEG and EEG to Source Orientation |
| title_fullStr | Sensitivity of MEG and EEG to Source Orientation |
| title_full_unstemmed | Sensitivity of MEG and EEG to Source Orientation |
| title_short | Sensitivity of MEG and EEG to Source Orientation |
| title_sort | sensitivity of meg and eeg to source orientation |
| url | http://hdl.handle.net/1721.1/64950 https://orcid.org/0000-0001-6841-112X |
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