Effective Size and Zeta Potential of Nanorods by Ferguson Analysis

The effective hydrodynamic size and free mobility of particles of varying aspect ratio were evaluated by Ferguson analysis of gel electrophoresis. The ligand layer thickness was estimated from the difference between the effective size and the size of the metal core from TEM imaging. The zeta potenti...

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Bibliographic Details
Main Authors: Park, Sunho, Sinha, Niraj, Hamad-Schifferli, Kimberly
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: American Chemical Society 2011
Online Access:http://hdl.handle.net/1721.1/65164
https://orcid.org/0000-0003-0874-4584
Description
Summary:The effective hydrodynamic size and free mobility of particles of varying aspect ratio were evaluated by Ferguson analysis of gel electrophoresis. The ligand layer thickness was estimated from the difference between the effective size and the size of the metal core from TEM imaging. The zeta potential of the particles was calculated from the Ferguson analysis result by applying conventional electrophoresis theories for spheres and cylinders. The results show that Henry’s solution for spherical particles can be used to obtain the zeta potential of cylindrical particles without requiring the use of TEM for size analysis.