Survey on indirect optical manipulation of cells, nucleic acids, and motor proteins
Optical tweezers have emerged as a promising technique for manipulating biological objects. Instead of direct laser exposure, more often than not, optically-trapped beads are attached to the ends or boundaries of the objects for translation, rotation, and stretching. This is referred to as indirect...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
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Society of Photo-optical Instrumentation Engineers
2011
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| Online Access: | http://hdl.handle.net/1721.1/65632 |
| _version_ | 1826192381826826240 |
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| author | Banerjee, Ashis Chowdhury, Sagar Losert, Wolfgang Gupta, Satyandra K. |
| author2 | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory |
| author_facet | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory Banerjee, Ashis Chowdhury, Sagar Losert, Wolfgang Gupta, Satyandra K. |
| author_sort | Banerjee, Ashis |
| collection | MIT |
| description | Optical tweezers have emerged as a promising technique for manipulating biological objects. Instead of direct laser exposure, more often than not, optically-trapped beads are attached to the ends or boundaries of the objects for translation, rotation, and stretching. This is referred to as indirect optical manipulation. In this paper, we utilize the concept of robotic gripping to explain the different experimental setups which are commonly used for indirect manipulation of cells, nucleic acids, and motor proteins. We also give an overview of the kind of biological insights provided by this technique. We conclude by highlighting the trends across the experimental studies, and discuss challenges and promising directions in this domain of active current research. |
| first_indexed | 2024-09-23T09:11:23Z |
| format | Article |
| id | mit-1721.1/65632 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T09:11:23Z |
| publishDate | 2011 |
| publisher | Society of Photo-optical Instrumentation Engineers |
| record_format | dspace |
| spelling | mit-1721.1/656322022-09-26T10:58:44Z Survey on indirect optical manipulation of cells, nucleic acids, and motor proteins Banerjee, Ashis Chowdhury, Sagar Losert, Wolfgang Gupta, Satyandra K. Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory Banerjee, Ashis Banerjee, Ashis Optical tweezers have emerged as a promising technique for manipulating biological objects. Instead of direct laser exposure, more often than not, optically-trapped beads are attached to the ends or boundaries of the objects for translation, rotation, and stretching. This is referred to as indirect optical manipulation. In this paper, we utilize the concept of robotic gripping to explain the different experimental setups which are commonly used for indirect manipulation of cells, nucleic acids, and motor proteins. We also give an overview of the kind of biological insights provided by this technique. We conclude by highlighting the trends across the experimental studies, and discuss challenges and promising directions in this domain of active current research. National Science Foundation (U.S.) (Grant No. CMMI- 0835572) National Science Foundation (U.S.) (CPS-0931508) 2011-09-09T18:37:04Z 2011-09-09T18:37:04Z 2011-05 2011-03 Article http://purl.org/eprint/type/JournalArticle 1083-3668 http://hdl.handle.net/1721.1/65632 Banerjee, Ashis Gopal et al. “Survey on indirect optical manipulation of cells, nucleic acids, and motor proteins.” Journal of Biomedical Optics 16 (2011): 051302. © 2011 Society of Photo-Optical Instrumentation Engineers. en_US http://dx.doi.org/10.1117/1.3579200 Journal of Biomedical Optics Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf Society of Photo-optical Instrumentation Engineers SPIE |
| spellingShingle | Banerjee, Ashis Chowdhury, Sagar Losert, Wolfgang Gupta, Satyandra K. Survey on indirect optical manipulation of cells, nucleic acids, and motor proteins |
| title | Survey on indirect optical manipulation of cells, nucleic acids, and motor proteins |
| title_full | Survey on indirect optical manipulation of cells, nucleic acids, and motor proteins |
| title_fullStr | Survey on indirect optical manipulation of cells, nucleic acids, and motor proteins |
| title_full_unstemmed | Survey on indirect optical manipulation of cells, nucleic acids, and motor proteins |
| title_short | Survey on indirect optical manipulation of cells, nucleic acids, and motor proteins |
| title_sort | survey on indirect optical manipulation of cells nucleic acids and motor proteins |
| url | http://hdl.handle.net/1721.1/65632 |
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