Speckle reduction in optical coherence tomography images using tissue viscoelasticity
We present a technique to reduce speckle in optical coherence tomography images of soft tissues. An average is formed over a set of B-scans that have been decorrelated by viscoelastic creep strain. The necessary correction for the deformation-induced spatial distortions between B-scans is achieved t...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Society of Photo-optical Instrumentation Engineers
2011
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| Online Access: | http://hdl.handle.net/1721.1/65634 |
| _version_ | 1826208402700763136 |
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| author | Kennedy, Brendan F. Curatolo, Andrea Sampson, David D. Hillman, Timothy Robert Saunders, Christobel M. |
| author2 | Massachusetts Institute of Technology. Spectroscopy Laboratory |
| author_facet | Massachusetts Institute of Technology. Spectroscopy Laboratory Kennedy, Brendan F. Curatolo, Andrea Sampson, David D. Hillman, Timothy Robert Saunders, Christobel M. |
| author_sort | Kennedy, Brendan F. |
| collection | MIT |
| description | We present a technique to reduce speckle in optical coherence tomography images of soft tissues. An average is formed over a set of B-scans that have been decorrelated by viscoelastic creep strain. The necessary correction for the deformation-induced spatial distortions between B-scans is achieved through geometrical co-registration using an affine transformation. Speckle reduction by up to a factor of 1.65 is shown in images of tissue-mimicking soft fibrin phantoms and excised human lymph node tissue with no observable loss of spatial resolution. |
| first_indexed | 2024-09-23T14:05:12Z |
| format | Article |
| id | mit-1721.1/65634 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T14:05:12Z |
| publishDate | 2011 |
| publisher | Society of Photo-optical Instrumentation Engineers |
| record_format | dspace |
| spelling | mit-1721.1/656342022-10-01T19:04:36Z Speckle reduction in optical coherence tomography images using tissue viscoelasticity Kennedy, Brendan F. Curatolo, Andrea Sampson, David D. Hillman, Timothy Robert Saunders, Christobel M. Massachusetts Institute of Technology. Spectroscopy Laboratory Hillman, Timothy Robert Hillman, Timothy Robert We present a technique to reduce speckle in optical coherence tomography images of soft tissues. An average is formed over a set of B-scans that have been decorrelated by viscoelastic creep strain. The necessary correction for the deformation-induced spatial distortions between B-scans is achieved through geometrical co-registration using an affine transformation. Speckle reduction by up to a factor of 1.65 is shown in images of tissue-mimicking soft fibrin phantoms and excised human lymph node tissue with no observable loss of spatial resolution. 2011-09-09T18:58:36Z 2011-09-09T18:58:36Z 2011-02 2011-01 Article http://purl.org/eprint/type/JournalArticle 1083-3668 http://hdl.handle.net/1721.1/65634 Kennedy, Brendan F. et al. “Speckle reduction in optical coherence tomography images using tissue viscoelasticity.” Journal of Biomedical Optics 16 (2011): 020506. © 2011 Society of Photo-Optical Instrumentation Engineers. en_US http://dx.doi.org/10.1117/1.3548239 Journal of Biomedical Optics Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf Society of Photo-optical Instrumentation Engineers SPIE |
| spellingShingle | Kennedy, Brendan F. Curatolo, Andrea Sampson, David D. Hillman, Timothy Robert Saunders, Christobel M. Speckle reduction in optical coherence tomography images using tissue viscoelasticity |
| title | Speckle reduction in optical coherence tomography images using tissue viscoelasticity |
| title_full | Speckle reduction in optical coherence tomography images using tissue viscoelasticity |
| title_fullStr | Speckle reduction in optical coherence tomography images using tissue viscoelasticity |
| title_full_unstemmed | Speckle reduction in optical coherence tomography images using tissue viscoelasticity |
| title_short | Speckle reduction in optical coherence tomography images using tissue viscoelasticity |
| title_sort | speckle reduction in optical coherence tomography images using tissue viscoelasticity |
| url | http://hdl.handle.net/1721.1/65634 |
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