DNA phosphorothioation is widespread and quantized in bacterial genomes
Phosphorothioate (PT) modification of DNA, with sulfur replacing a nonbridging phosphate oxygen, was recently discovered as a product of the dnd genes found in bacteria and archaea. Given our limited understanding of the biological function of PT modifications, including sequence context, genomic fr...
Main Authors: | Wang, Lianrong, Chen, Shi, Vergin, Kevin L., Giovannoni, Stephen J., Chan, Simon W., DeMott, Michael S., Taghizadeh, Koli, Cordero Sanchez, Otto Xavier, Cutler, Michael Barry, Timberlake, Sonia, Alm, Eric J., Polz, Martin F., Pinhassi, Jarone, Deng, Zixin, Dedon, Peter C. |
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Other Authors: | Massachusetts Institute of Technology. Center for Environmental Health Sciences |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences
2011
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Online Access: | http://hdl.handle.net/1721.1/66131 https://orcid.org/0000-0001-8294-9364 https://orcid.org/0000-0003-0011-3067 https://orcid.org/0000-0001-9296-3733 https://orcid.org/0000-0002-4607-5337 |
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