Imaging mesoscopic nuclear spin noise with a diamond magnetometer
Magnetic resonance imaging can characterize and discriminate among tissues using their diverse physical and biochemical properties. Unfortunately, submicrometer screening of biological specimens is presently not possible, mainly due to lack of detection sensitivity. Here we analyze the use of a nitr...
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| Format: | Article |
| Language: | en_US |
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American Institute of Physics
2011
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| Online Access: | http://hdl.handle.net/1721.1/66210 https://orcid.org/0000-0003-3207-594X https://orcid.org/0000-0002-3969-3604 |
| _version_ | 1826214616529633280 |
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| author | Meriles, Carlos A. Jiang, Liang Goldstein, Garry Hodges, Jonathan S. Maze, Jeronimo R. Lukin, Mikhail D. Cappellaro, Paola |
| author2 | Massachusetts Institute of Technology. Department of Nuclear Science and Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Nuclear Science and Engineering Meriles, Carlos A. Jiang, Liang Goldstein, Garry Hodges, Jonathan S. Maze, Jeronimo R. Lukin, Mikhail D. Cappellaro, Paola |
| author_sort | Meriles, Carlos A. |
| collection | MIT |
| description | Magnetic resonance imaging can characterize and discriminate among tissues using their diverse physical and biochemical properties. Unfortunately, submicrometer screening of biological specimens is presently not possible, mainly due to lack of detection sensitivity. Here we analyze the use of a nitrogen-vacancy center in diamond as a magnetic sensor for nanoscale nuclear spin imaging and spectroscopy. We examine the ability of such a sensor to probe the fluctuations of the “classical” dipolar field due to a large number of neighboring nuclear spins in a densely protonated sample. We identify detection protocols that appropriately take into account the quantum character of the sensor and find a signal-to-noise ratio compatible with realistic experimental parameters. Through various example calculations we illustrate different kinds of image contrast. In particular, we show how to exploit the comparatively long nuclear spin correlation times to reconstruct a local, high-resolution sample spectrum. |
| first_indexed | 2024-09-23T16:08:38Z |
| format | Article |
| id | mit-1721.1/66210 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T16:08:38Z |
| publishDate | 2011 |
| publisher | American Institute of Physics |
| record_format | dspace |
| spelling | mit-1721.1/662102022-10-02T06:36:43Z Imaging mesoscopic nuclear spin noise with a diamond magnetometer Meriles, Carlos A. Jiang, Liang Goldstein, Garry Hodges, Jonathan S. Maze, Jeronimo R. Lukin, Mikhail D. Cappellaro, Paola Massachusetts Institute of Technology. Department of Nuclear Science and Engineering Cappellaro, Paola Hodges, Jonathan S. Cappellaro, Paola Magnetic resonance imaging can characterize and discriminate among tissues using their diverse physical and biochemical properties. Unfortunately, submicrometer screening of biological specimens is presently not possible, mainly due to lack of detection sensitivity. Here we analyze the use of a nitrogen-vacancy center in diamond as a magnetic sensor for nanoscale nuclear spin imaging and spectroscopy. We examine the ability of such a sensor to probe the fluctuations of the “classical” dipolar field due to a large number of neighboring nuclear spins in a densely protonated sample. We identify detection protocols that appropriately take into account the quantum character of the sensor and find a signal-to-noise ratio compatible with realistic experimental parameters. Through various example calculations we illustrate different kinds of image contrast. In particular, we show how to exploit the comparatively long nuclear spin correlation times to reconstruct a local, high-resolution sample spectrum. National Institute of Standards and Technology (U.S.) (Award # 60NANB10D002) 2011-10-11T20:50:38Z 2011-10-11T20:50:38Z 2010-09 2010-04 Article http://purl.org/eprint/type/JournalArticle 0021-9606 http://hdl.handle.net/1721.1/66210 Meriles, Carlos A. et al. “Imaging mesoscopic nuclear spin noise with a diamond magnetometer.” The Journal of Chemical Physics 133, 124105 (2010): 124105. © 2010 American Institute of Physics https://orcid.org/0000-0003-3207-594X https://orcid.org/0000-0002-3969-3604 en_US http://dx.doi.org/10.1063/1.3483676 Journal of Chemical Physics Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf American Institute of Physics AIP |
| spellingShingle | Meriles, Carlos A. Jiang, Liang Goldstein, Garry Hodges, Jonathan S. Maze, Jeronimo R. Lukin, Mikhail D. Cappellaro, Paola Imaging mesoscopic nuclear spin noise with a diamond magnetometer |
| title | Imaging mesoscopic nuclear spin noise with a diamond magnetometer |
| title_full | Imaging mesoscopic nuclear spin noise with a diamond magnetometer |
| title_fullStr | Imaging mesoscopic nuclear spin noise with a diamond magnetometer |
| title_full_unstemmed | Imaging mesoscopic nuclear spin noise with a diamond magnetometer |
| title_short | Imaging mesoscopic nuclear spin noise with a diamond magnetometer |
| title_sort | imaging mesoscopic nuclear spin noise with a diamond magnetometer |
| url | http://hdl.handle.net/1721.1/66210 https://orcid.org/0000-0003-3207-594X https://orcid.org/0000-0002-3969-3604 |
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