Reassessment of the Lineage Fusion Hypothesis for the Origin of Double Membrane Bacteria
In 2009, James Lake introduced a new hypothesis in which reticulate phylogeny reconstruction is used to elucidate the origin of Gram-negative bacteria (Nature 460: 967–971). The presented data supported the Gram-negative bacteria originating from an ancient endosymbiosis between the Actinobacteria a...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | en_US |
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Public Library of Science
2011
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| Online Access: | http://hdl.handle.net/1721.1/66213 https://orcid.org/0000-0003-1605-5455 |
| _version_ | 1811097260825509888 |
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| author | Swithers, Kristen S. Fournier, Gregory P. Green, Anna G. Gogarten, J. Peter Lapierre, Pascal |
| author2 | Massachusetts Institute of Technology. Department of Biological Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Biological Engineering Swithers, Kristen S. Fournier, Gregory P. Green, Anna G. Gogarten, J. Peter Lapierre, Pascal |
| author_sort | Swithers, Kristen S. |
| collection | MIT |
| description | In 2009, James Lake introduced a new hypothesis in which reticulate phylogeny reconstruction is used to elucidate the origin of Gram-negative bacteria (Nature 460: 967–971). The presented data supported the Gram-negative bacteria originating from an ancient endosymbiosis between the Actinobacteria and Clostridia. His conclusion was based on a presence-absence analysis of protein families that divided all prokaryotes into five groups: Actinobacteria, Double Membrane bacteria (DM), Clostridia, Archaea and Bacilli. Of these five groups, the DM are by far the largest and most diverse group compared to the other groupings. While the fusion hypothesis for the origin of double membrane bacteria is enticing, we show that the signal supporting an ancient symbiosis is lost when the DM group is broken down into smaller subgroups. We conclude that the signal detected in James Lake's analysis in part results from a systematic artifact due to group size and diversity combined with low levels of horizontal gene transfer. |
| first_indexed | 2024-09-23T16:56:56Z |
| format | Article |
| id | mit-1721.1/66213 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T16:56:56Z |
| publishDate | 2011 |
| publisher | Public Library of Science |
| record_format | dspace |
| spelling | mit-1721.1/662132022-09-29T22:34:33Z Reassessment of the Lineage Fusion Hypothesis for the Origin of Double Membrane Bacteria Swithers, Kristen S. Fournier, Gregory P. Green, Anna G. Gogarten, J. Peter Lapierre, Pascal Massachusetts Institute of Technology. Department of Biological Engineering Massachusetts Institute of Technology. Department of Civil and Environmental Engineering Fournier, Gregory P. Fournier, Gregory P. In 2009, James Lake introduced a new hypothesis in which reticulate phylogeny reconstruction is used to elucidate the origin of Gram-negative bacteria (Nature 460: 967–971). The presented data supported the Gram-negative bacteria originating from an ancient endosymbiosis between the Actinobacteria and Clostridia. His conclusion was based on a presence-absence analysis of protein families that divided all prokaryotes into five groups: Actinobacteria, Double Membrane bacteria (DM), Clostridia, Archaea and Bacilli. Of these five groups, the DM are by far the largest and most diverse group compared to the other groupings. While the fusion hypothesis for the origin of double membrane bacteria is enticing, we show that the signal supporting an ancient symbiosis is lost when the DM group is broken down into smaller subgroups. We conclude that the signal detected in James Lake's analysis in part results from a systematic artifact due to group size and diversity combined with low levels of horizontal gene transfer. Exobiology Program (U.S.) (Grant NNX08AQ10G) Assembling the Tree of Life (Program) (Grant DEB 0830024) 2011-10-11T21:27:05Z 2011-10-11T21:27:05Z 2011-08 2011-05 Article http://purl.org/eprint/type/JournalArticle 1932-6203 http://hdl.handle.net/1721.1/66213 Swithers, Kristen S. et al. “Reassessment of the Lineage Fusion Hypothesis for the Origin of Double Membrane Bacteria.” Ed. Jonathan H. Badger. PLoS ONE 6 (8) (2011): e23774. © 2011 Swithers et al. https://orcid.org/0000-0003-1605-5455 en_US http://dx.doi.org/10.1371/journal.pone.0023774 PLoS ONE Creative Commons Attribution http://creativecommons.org/licenses/by/2.5/ application/pdf Public Library of Science PLoS |
| spellingShingle | Swithers, Kristen S. Fournier, Gregory P. Green, Anna G. Gogarten, J. Peter Lapierre, Pascal Reassessment of the Lineage Fusion Hypothesis for the Origin of Double Membrane Bacteria |
| title | Reassessment of the Lineage Fusion Hypothesis for the Origin of Double Membrane Bacteria |
| title_full | Reassessment of the Lineage Fusion Hypothesis for the Origin of Double Membrane Bacteria |
| title_fullStr | Reassessment of the Lineage Fusion Hypothesis for the Origin of Double Membrane Bacteria |
| title_full_unstemmed | Reassessment of the Lineage Fusion Hypothesis for the Origin of Double Membrane Bacteria |
| title_short | Reassessment of the Lineage Fusion Hypothesis for the Origin of Double Membrane Bacteria |
| title_sort | reassessment of the lineage fusion hypothesis for the origin of double membrane bacteria |
| url | http://hdl.handle.net/1721.1/66213 https://orcid.org/0000-0003-1605-5455 |
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