Cortical network dynamics of perceptual decision-making in the human brain
Goal-directed behavior requires the flexible transformation of sensory evidence about our environment into motor actions. Studies of perceptual decision-making have shown that this transformation is distributed across several widely separated brain regions. Yet, little is known about how decision-ma...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
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Frontiers Media S.A.
2011
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| Online Access: | http://hdl.handle.net/1721.1/66240 |
| _version_ | 1826202221089390592 |
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| author | Siegel, Markus Engel, Andreas K. Donner, Tobias H. |
| author2 | Picower Institute for Learning and Memory |
| author_facet | Picower Institute for Learning and Memory Siegel, Markus Engel, Andreas K. Donner, Tobias H. |
| author_sort | Siegel, Markus |
| collection | MIT |
| description | Goal-directed behavior requires the flexible transformation of sensory evidence about our environment into motor actions. Studies of perceptual decision-making have shown that this transformation is distributed across several widely separated brain regions. Yet, little is known about how decision-making emerges from the dynamic interactions among these regions. Here, we review a series of studies, in which we characterized the cortical network interactions underlying a perceptual decision process in the human brain. We used magnetoencephalography to measure the large-scale cortical population dynamics underlying each of the sub-processes involved in this decision: the encoding of sensory evidence and action plan, the mapping between the two, and the attentional selection of task-relevant evidence. We found that these sub-processes are mediated by neuronal oscillations within specific frequency ranges. Localized gamma-band oscillations in sensory and motor cortices reflect the encoding of the sensory evidence and motor plan. Large-scale oscillations across widespread cortical networks mediate the integrative processes connecting these local networks: Gamma- and beta-band oscillations across frontal, parietal, and sensory cortices serve the selection of relevant sensory evidence and its flexible mapping onto action plans. In sum, our results suggest that perceptual decisions are mediated by oscillatory interactions within overlapping local and large-scale cortical networks. |
| first_indexed | 2024-09-23T12:04:05Z |
| format | Article |
| id | mit-1721.1/66240 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T12:04:05Z |
| publishDate | 2011 |
| publisher | Frontiers Media S.A. |
| record_format | dspace |
| spelling | mit-1721.1/662402022-10-01T07:55:58Z Cortical network dynamics of perceptual decision-making in the human brain Siegel, Markus Engel, Andreas K. Donner, Tobias H. Picower Institute for Learning and Memory Siegel, Markus Siegel, Markus Goal-directed behavior requires the flexible transformation of sensory evidence about our environment into motor actions. Studies of perceptual decision-making have shown that this transformation is distributed across several widely separated brain regions. Yet, little is known about how decision-making emerges from the dynamic interactions among these regions. Here, we review a series of studies, in which we characterized the cortical network interactions underlying a perceptual decision process in the human brain. We used magnetoencephalography to measure the large-scale cortical population dynamics underlying each of the sub-processes involved in this decision: the encoding of sensory evidence and action plan, the mapping between the two, and the attentional selection of task-relevant evidence. We found that these sub-processes are mediated by neuronal oscillations within specific frequency ranges. Localized gamma-band oscillations in sensory and motor cortices reflect the encoding of the sensory evidence and motor plan. Large-scale oscillations across widespread cortical networks mediate the integrative processes connecting these local networks: Gamma- and beta-band oscillations across frontal, parietal, and sensory cortices serve the selection of relevant sensory evidence and its flexible mapping onto action plans. In sum, our results suggest that perceptual decisions are mediated by oscillatory interactions within overlapping local and large-scale cortical networks. European Union ((NEST-PATH-043457) European Union (HEALTH-F2-2008-200728) Deutsche Forschungsgemeinschaft (GRK 1247/1/2, SFB TRR58) Germany. Federal Ministry of Education and Research (01GW0561, Neuroimage Nord) German Academy of Sciences Leopoldina (THD: BMBF-LPD 9901/8-136) 2011-10-13T15:33:00Z 2011-10-13T15:33:00Z 2011-02 2010-06 Article http://purl.org/eprint/type/JournalArticle 1662-5161 http://hdl.handle.net/1721.1/66240 Siegel, Markus, Andreas K. Engel, and Tobias H. Donner. “Cortical Network Dynamics of Perceptual Decision-Making in the Human Brain.” Frontiers in Human Neuroscience 5 (2011). ©2011 Frontiers Media S.A. en_US http://dx.doi.org/10.3389/fnhum.2011.00021 Frontiers in Human Neuroscience Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf Frontiers Media S.A. Frontiers |
| spellingShingle | Siegel, Markus Engel, Andreas K. Donner, Tobias H. Cortical network dynamics of perceptual decision-making in the human brain |
| title | Cortical network dynamics of perceptual decision-making in the human brain |
| title_full | Cortical network dynamics of perceptual decision-making in the human brain |
| title_fullStr | Cortical network dynamics of perceptual decision-making in the human brain |
| title_full_unstemmed | Cortical network dynamics of perceptual decision-making in the human brain |
| title_short | Cortical network dynamics of perceptual decision-making in the human brain |
| title_sort | cortical network dynamics of perceptual decision making in the human brain |
| url | http://hdl.handle.net/1721.1/66240 |
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