Widespread Brain Areas Engaged during a Classical Auditory Streaming Task Revealed by Intracranial EEG
The auditory system must constantly decompose the complex mixture of sound arriving at the ear into perceptually independent streams constituting accurate representations of individual sources in the acoustic environment. How the brain accomplishes this task is not well understood. The present study...
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| Format: | Article |
| Language: | en_US |
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Frontiers Media S.A.
2011
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| Online Access: | http://hdl.handle.net/1721.1/66253 |
| _version_ | 1826188155405991936 |
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| author | Dykstra, Andrew Richard Halgren, Eric Thesen, Thomas Carlson, Chad E. Doyle, Werner Madsen, Joseph R. Eskandar, Emad Cash, Sydney S. |
| author2 | Harvard University--MIT Division of Health Sciences and Technology |
| author_facet | Harvard University--MIT Division of Health Sciences and Technology Dykstra, Andrew Richard Halgren, Eric Thesen, Thomas Carlson, Chad E. Doyle, Werner Madsen, Joseph R. Eskandar, Emad Cash, Sydney S. |
| author_sort | Dykstra, Andrew Richard |
| collection | MIT |
| description | The auditory system must constantly decompose the complex mixture of sound arriving at the ear into perceptually independent streams constituting accurate representations of individual sources in the acoustic environment. How the brain accomplishes this task is not well understood. The present study combined a classic behavioral paradigm with direct cortical recordings from neurosurgical patients with epilepsy in order to further describe the neural correlates of auditory streaming. Participants listened to sequences of pure tones alternating in frequency and indicated whether they heard one or two “streams.” The intracranial EEG was simultaneously recorded from sub-dural electrodes placed over temporal, frontal, and parietal cortex. Like healthy subjects, patients heard one stream when the frequency separation between tones was small and two when it was large. Robust evoked-potential correlates of frequency separation were observed over widespread brain areas. Waveform morphology was highly variable across individual electrode sites both within and across gross brain regions. Surprisingly, few evoked-potential correlates of perceptual organization were observed after controlling for physical stimulus differences. The results indicate that the cortical areas engaged during the streaming task are more complex and widespread than has been demonstrated by previous work, and that, by-and-large, correlates of bistability during streaming are probably located on a spatial scale not assessed – or in a brain area not examined – by the present study. |
| first_indexed | 2024-09-23T07:55:24Z |
| format | Article |
| id | mit-1721.1/66253 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T07:55:24Z |
| publishDate | 2011 |
| publisher | Frontiers Media S.A. |
| record_format | dspace |
| spelling | mit-1721.1/662532022-09-30T01:00:39Z Widespread Brain Areas Engaged during a Classical Auditory Streaming Task Revealed by Intracranial EEG Dykstra, Andrew Richard Halgren, Eric Thesen, Thomas Carlson, Chad E. Doyle, Werner Madsen, Joseph R. Eskandar, Emad Cash, Sydney S. Harvard University--MIT Division of Health Sciences and Technology Dykstra, Andrew Richard Dykstra, Andrew Richard The auditory system must constantly decompose the complex mixture of sound arriving at the ear into perceptually independent streams constituting accurate representations of individual sources in the acoustic environment. How the brain accomplishes this task is not well understood. The present study combined a classic behavioral paradigm with direct cortical recordings from neurosurgical patients with epilepsy in order to further describe the neural correlates of auditory streaming. Participants listened to sequences of pure tones alternating in frequency and indicated whether they heard one or two “streams.” The intracranial EEG was simultaneously recorded from sub-dural electrodes placed over temporal, frontal, and parietal cortex. Like healthy subjects, patients heard one stream when the frequency separation between tones was small and two when it was large. Robust evoked-potential correlates of frequency separation were observed over widespread brain areas. Waveform morphology was highly variable across individual electrode sites both within and across gross brain regions. Surprisingly, few evoked-potential correlates of perceptual organization were observed after controlling for physical stimulus differences. The results indicate that the cortical areas engaged during the streaming task are more complex and widespread than has been demonstrated by previous work, and that, by-and-large, correlates of bistability during streaming are probably located on a spatial scale not assessed – or in a brain area not examined – by the present study. National Institute on Deafness and Other Communication Disorders (U.S.) (grant T32 DC00038) National Institute of Biomedical Imaging and Bioengineering (U.S.) (grant T32 EB001680) Amelia Peabody Charitable Trust National Institutes of Health (U.S.) (NIH grant NS18741) National Institute of Neurological Disorders and Stroke (U.S.) (NINDS grant NS062092) 2011-10-14T18:31:01Z 2011-10-14T18:31:01Z 2011-08 2011-05 Article http://purl.org/eprint/type/JournalArticle 1662-5161 http://hdl.handle.net/1721.1/66253 Dykstra, Andrew R. et al. “Widespread Brain Areas Engaged during a Classical Auditory Streaming Task Revealed by Intracranial EEG.” Frontiers in Human Neuroscience 5 (2011). en_US http://dx.doi.org/10.3389/fnhum.2011.00074 Frontiers in Human Neuroscience Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf Frontiers Media S.A. Frontiers |
| spellingShingle | Dykstra, Andrew Richard Halgren, Eric Thesen, Thomas Carlson, Chad E. Doyle, Werner Madsen, Joseph R. Eskandar, Emad Cash, Sydney S. Widespread Brain Areas Engaged during a Classical Auditory Streaming Task Revealed by Intracranial EEG |
| title | Widespread Brain Areas Engaged during a Classical Auditory Streaming Task Revealed by Intracranial EEG |
| title_full | Widespread Brain Areas Engaged during a Classical Auditory Streaming Task Revealed by Intracranial EEG |
| title_fullStr | Widespread Brain Areas Engaged during a Classical Auditory Streaming Task Revealed by Intracranial EEG |
| title_full_unstemmed | Widespread Brain Areas Engaged during a Classical Auditory Streaming Task Revealed by Intracranial EEG |
| title_short | Widespread Brain Areas Engaged during a Classical Auditory Streaming Task Revealed by Intracranial EEG |
| title_sort | widespread brain areas engaged during a classical auditory streaming task revealed by intracranial eeg |
| url | http://hdl.handle.net/1721.1/66253 |
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