Metal-substituted protein MRI contrast agents engineered for enhanced relaxivity and ligand sensitivity
Engineered metalloproteins constitute a flexible new class of analyte-sensitive molecular imaging agents detectable by magnetic resonance imaging (MRI), but their contrast effects are generally weaker than synthetic agents. To augment the proton relaxivity of agents derived from the heme domain of c...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
American Chemical Society
2011
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| Online Access: | http://hdl.handle.net/1721.1/66550 https://orcid.org/0000-0002-2834-6359 https://orcid.org/0000-0002-3890-0288 |