Splice site strength–dependent activity and genetic buffering by poly-G runs
Pre-mRNA splicing is regulated through the combinatorial activity of RNA motifs, including splice sites and splicing regulatory elements. Here we show that the activity of the G-run (polyguanine sequence) class of splicing enhancer elements is approx4-fold higher when adjacent to intermediate streng...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Nature Publishing Group
2011
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| Online Access: | http://hdl.handle.net/1721.1/66571 https://orcid.org/0000-0002-6605-3637 |