PSD-95 Is Required to Sustain the Molecular Organization of the Postsynaptic Density

PSD-95 Is Required to Sustain the Molecular Organization of the Postsynaptic Density

PSD-95, a membrane-associated guanylate kinase, is the major scaffolding protein in the excitatory postsynaptic density (PSD) and a potent regulator of synaptic strength. Here we show that PSD-95 is in an extended configuration and positioned into regular arrays of vertical filaments that contact bo...

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Bibliographic Details
Main Authors: Chen, Xiaobing, Nelson, Christopher D., Li, Xiang, Winters, Christine A., Azzam, Rita, Sousa, Alioscka A., Leapman, Richard D., Gainer, Harold, Sheng, Morgan Hwa-Tze, Reese, Thomas S.
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: Society for Neuroscience 2011
Online Access:http://hdl.handle.net/1721.1/66976

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http://hdl.handle.net/1721.1/66976

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