Adult bone marrow stromal cell-based tissue-engineered aggrecan exhibits ultrastructure and nanomechanical properties superior to native cartilage

Adult bone marrow stromal cell-based tissue-engineered aggrecan exhibits ultrastructure and nanomechanical properties superior to native cartilage

Objective: To quantify the structural characteristics and nanomechanical properties of aggrecan produced by adult bone marrow stromal cells (BMSCs) in peptide hydrogel scaffolds and compare to aggrecan from adult articular cartilage. Design: Adult equine BMSCs were encapsulated in 3D-peptide...

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Bibliographic Details
Main Authors:	Lee, H.-Y., Kopesky, Paul Wayne, Plaas, A., Sandy, J., Kisiday, John D., Frisbie, David D., Grodzinsky, Alan J., Ortiz, Christine
Other Authors:	Massachusetts Institute of Technology. Center for Biomedical Engineering
Format:	Article
Language:	en_US
Published:	Elsevier Ltd. 2011
Online Access:	http://hdl.handle.net/1721.1/67287 https://orcid.org/0000-0003-3511-5679 https://orcid.org/0000-0003-0026-6215 https://orcid.org/0000-0002-4942-3456

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