A Magnetic Retrieval System for Stents in the Pancreaticobiliary Tree
Clinical endoscopic intervention of the pancreaticobiliary tree [endoscopic retrograde cholangiopancreatography (ERCP)] often concludes with the insertion of a temporary plastic stent to reduce the risk of post-ERCP complications by promoting continued flow of bile and pancreatic fluids. This stent...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | en_US |
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Institute of Electrical and Electronics Engineers
2011
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| Online Access: | http://hdl.handle.net/1721.1/67500 https://orcid.org/0000-0002-5765-4369 https://orcid.org/0000-0001-6679-2889 |
| _version_ | 1811078204543205376 |
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| author | Cantillon-Murphy, Padraig Ryou, Marvin Shaikh, Sohail N. Azagury, Dan Ryan, Michele Thompson, Christopher C. Lang, Jeffrey H. |
| author2 | Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science |
| author_facet | Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Cantillon-Murphy, Padraig Ryou, Marvin Shaikh, Sohail N. Azagury, Dan Ryan, Michele Thompson, Christopher C. Lang, Jeffrey H. |
| author_sort | Cantillon-Murphy, Padraig |
| collection | MIT |
| description | Clinical endoscopic intervention of the pancreaticobiliary tree [endoscopic retrograde cholangiopancreatography (ERCP)] often concludes with the insertion of a temporary plastic stent to reduce the risk of post-ERCP complications by promoting continued flow of bile and pancreatic fluids. This stent is later removed once the patient has fully recovered, but today this necessitates a second endoscopic intervention. The final goal of this work is to obviate the second intervention. This is to be achieved by adding a magnetic ring to the stent such that the stent is removed using a hand-held magnet, held in a suitable position ex vivo . This paper details the design, optimization, and both ex vivo and in vivo testing of the magnetized stent and hand-held magnet, which has been accomplished to date. The optimized design for the hand-held magnet and the modified stent with a magnetic attachment performs in line with simulated expectations, and successful retrieval is achieved in the porcine ex vivo setting at 9-10 cm separation. This is comparable to the mean target capture distance of 10 cm between the entry point to the biliary system and the closest cutaneous surface, determined from random review of clinical fluoroscopies in ten human patients. Subsequently, the system was successfully tested in vivo in the acute porcine model, where retrieval at an estimated separation of 5-6 cm was captured on endoscopic video. These initial results indicate that the system may represent a promising approach for the elimination of a second endoscopic procedures following placement of pancreatic and biliary stents. |
| first_indexed | 2024-09-23T10:55:35Z |
| format | Article |
| id | mit-1721.1/67500 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T10:55:35Z |
| publishDate | 2011 |
| publisher | Institute of Electrical and Electronics Engineers |
| record_format | dspace |
| spelling | mit-1721.1/675002022-09-30T23:57:29Z A Magnetic Retrieval System for Stents in the Pancreaticobiliary Tree Cantillon-Murphy, Padraig Ryou, Marvin Shaikh, Sohail N. Azagury, Dan Ryan, Michele Thompson, Christopher C. Lang, Jeffrey H. Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Lang, Jeffrey H. Lang, Jeffrey H. Cantillon-Murphy, Padraig Clinical endoscopic intervention of the pancreaticobiliary tree [endoscopic retrograde cholangiopancreatography (ERCP)] often concludes with the insertion of a temporary plastic stent to reduce the risk of post-ERCP complications by promoting continued flow of bile and pancreatic fluids. This stent is later removed once the patient has fully recovered, but today this necessitates a second endoscopic intervention. The final goal of this work is to obviate the second intervention. This is to be achieved by adding a magnetic ring to the stent such that the stent is removed using a hand-held magnet, held in a suitable position ex vivo . This paper details the design, optimization, and both ex vivo and in vivo testing of the magnetized stent and hand-held magnet, which has been accomplished to date. The optimized design for the hand-held magnet and the modified stent with a magnetic attachment performs in line with simulated expectations, and successful retrieval is achieved in the porcine ex vivo setting at 9-10 cm separation. This is comparable to the mean target capture distance of 10 cm between the entry point to the biliary system and the closest cutaneous surface, determined from random review of clinical fluoroscopies in ten human patients. Subsequently, the system was successfully tested in vivo in the acute porcine model, where retrieval at an estimated separation of 5-6 cm was captured on endoscopic video. These initial results indicate that the system may represent a promising approach for the elimination of a second endoscopic procedures following placement of pancreatic and biliary stents. 2011-12-09T20:28:32Z 2011-12-09T20:28:32Z 2010-08 2010-01 Article http://purl.org/eprint/type/JournalArticle 0018-9294 INSPEC Accession Number: 11510525 http://hdl.handle.net/1721.1/67500 Cantillon-Murphy, P. et al. “A Magnetic Retrieval System for Stents in the Pancreaticobiliary Tree.” Biomedical Engineering, IEEE Transactions on 57.8 (2010): 2018-2025. © 2011 IEEE. PubMed ID: 20483696 https://orcid.org/0000-0002-5765-4369 https://orcid.org/0000-0001-6679-2889 en_US http://dx.doi.org/10.1109/tbme.2010.2045653 IEEE Transactions on Biomedical Engineering Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf Institute of Electrical and Electronics Engineers IEEE |
| spellingShingle | Cantillon-Murphy, Padraig Ryou, Marvin Shaikh, Sohail N. Azagury, Dan Ryan, Michele Thompson, Christopher C. Lang, Jeffrey H. A Magnetic Retrieval System for Stents in the Pancreaticobiliary Tree |
| title | A Magnetic Retrieval System for Stents in the Pancreaticobiliary Tree |
| title_full | A Magnetic Retrieval System for Stents in the Pancreaticobiliary Tree |
| title_fullStr | A Magnetic Retrieval System for Stents in the Pancreaticobiliary Tree |
| title_full_unstemmed | A Magnetic Retrieval System for Stents in the Pancreaticobiliary Tree |
| title_short | A Magnetic Retrieval System for Stents in the Pancreaticobiliary Tree |
| title_sort | magnetic retrieval system for stents in the pancreaticobiliary tree |
| url | http://hdl.handle.net/1721.1/67500 https://orcid.org/0000-0002-5765-4369 https://orcid.org/0000-0001-6679-2889 |
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