Nickel/Bis(oxazoline)-Catalyzed Asymmetric Kumada Reactions of Alkyl Electrophiles: Cross-Couplings of Racemic alpha-Bromoketones

Nickel/Bis(oxazoline)-Catalyzed Asymmetric Kumada Reactions of Alkyl Electrophiles: Cross-Couplings of Racemic alpha-Bromoketones

The first asymmetric Kumada reactions of alkyl electrophiles are described, specifically, cross-couplings of racemic α-bromoketones with aryl Grignard reagents. Several features of this investigation are of interest. First, the couplings proceed at remarkably low temperature (−40 or −60 °C), which e...

Полное описание

Библиографические подробности
Главные авторы:	Lou, Sha, Fu, Gregory C.
Другие авторы:	Massachusetts Institute of Technology. Department of Chemistry
Формат:	Статья
Язык:	en_US
Опубликовано:	American Chemical Society 2011
Online-ссылка:	http://hdl.handle.net/1721.1/67688

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