A research-inspired laboratory sequence investigating acquired drug resistance

Here, we present a six-session laboratory exercise designed to introduce students to standard biochemical techniques in the context of investigating a high impact research topic, acquired resistance to the cancer drug Gleevec. Students express a Gleevec-resistant mutant of the Abelson tyrosine kinas...

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Bibliographic Details
Main Authors: Taylor, Elizabeth Vogel, Fortune, Jennifer A., Drennan, Catherine L
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: John Wiley & Sons 2011
Online Access:http://hdl.handle.net/1721.1/67825
https://orcid.org/0000-0001-5486-2755
https://orcid.org/0000-0002-8121-9519