The Role of Chemical Mechanisms in Neural Computation and Learning
Most computational models of neurons assume that their electrical characteristics are of paramount importance. However, all long-term changes in synaptic efficacy, as well as many short-term effects, are mediated by chemical mechanisms. This technical report explores the interaction between ele...
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| Language: | en_US |
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2004
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| Online Access: | http://hdl.handle.net/1721.1/6786 |
| _version_ | 1826207305771778048 |
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| author | Hiller, Martha J. |
| author_facet | Hiller, Martha J. |
| author_sort | Hiller, Martha J. |
| collection | MIT |
| description | Most computational models of neurons assume that their electrical characteristics are of paramount importance. However, all long-term changes in synaptic efficacy, as well as many short-term effects, are mediated by chemical mechanisms. This technical report explores the interaction between electrical and chemical mechanisms in neural learning and development. Two neural systems that exemplify this interaction are described and modelled. The first is the mechanisms underlying habituation, sensitization, and associative learning in the gill withdrawal reflex circuit in Aplysia, a marine snail. The second is the formation of retinotopic projections in the early visual pathway during embryonic development. |
| first_indexed | 2024-09-23T13:47:15Z |
| id | mit-1721.1/6786 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T13:47:15Z |
| publishDate | 2004 |
| record_format | dspace |
| spelling | mit-1721.1/67862019-04-12T08:32:17Z The Role of Chemical Mechanisms in Neural Computation and Learning Hiller, Martha J. visual system development learning mechanisms synaptic learning mechanisms Most computational models of neurons assume that their electrical characteristics are of paramount importance. However, all long-term changes in synaptic efficacy, as well as many short-term effects, are mediated by chemical mechanisms. This technical report explores the interaction between electrical and chemical mechanisms in neural learning and development. Two neural systems that exemplify this interaction are described and modelled. The first is the mechanisms underlying habituation, sensitization, and associative learning in the gill withdrawal reflex circuit in Aplysia, a marine snail. The second is the formation of retinotopic projections in the early visual pathway during embryonic development. 2004-10-20T19:55:00Z 2004-10-20T19:55:00Z 1995-05-23 AITR-1455 http://hdl.handle.net/1721.1/6786 en_US AITR-1455 133 p. 1418693 bytes 1755787 bytes application/octet-stream application/pdf application/octet-stream application/pdf |
| spellingShingle | visual system development learning mechanisms synaptic learning mechanisms Hiller, Martha J. The Role of Chemical Mechanisms in Neural Computation and Learning |
| title | The Role of Chemical Mechanisms in Neural Computation and Learning |
| title_full | The Role of Chemical Mechanisms in Neural Computation and Learning |
| title_fullStr | The Role of Chemical Mechanisms in Neural Computation and Learning |
| title_full_unstemmed | The Role of Chemical Mechanisms in Neural Computation and Learning |
| title_short | The Role of Chemical Mechanisms in Neural Computation and Learning |
| title_sort | role of chemical mechanisms in neural computation and learning |
| topic | visual system development learning mechanisms synaptic learning mechanisms |
| url | http://hdl.handle.net/1721.1/6786 |
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