Complex receptor-ligand dynamics control the response of the VEGF system to protease injury

Complex receptor-ligand dynamics control the response of the VEGF system to protease injury

Background Vascular homeostasis and response to injury are dependent on the coordinated activity of growth factors such as vascular endothelial growth factor-A (VEGF). VEGF signaling is mediated by VEGF receptors 1 (VEGFR1) and 2 (VEGFR2). VEGF also binds to extracellular matrix (ECM) and neuropilin...

Full description

Bibliographic Details
Main Authors: Forsten-Williams, Kimberly, Kurtagic, Elma, Nugent, Matthew A.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:English
Published: BioMed Central Ltd 2012
Online Access:http://hdl.handle.net/1721.1/69072

Similar Items

Similar Items