A Conserved PHD Finger Protein and Endogenous RNAi Modulate Insulin Signaling in Caenorhabditis elegans

A Conserved PHD Finger Protein and Endogenous RNAi Modulate Insulin Signaling in Caenorhabditis elegans

Insulin signaling has a profound effect on longevity and the oxidative stress resistance of animals. Inhibition of insulin signaling results in the activation of DAF-16/FOXO and SKN-1/Nrf transcription factors and increased animal fitness. By studying the biological functions of the endogenous RNA i...

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Bibliographic Details
Main Authors: Mansisidor, Andres R., Cecere, Germano, Hoersch, Sebastian, Jensen, Morten B., Kawli, Trupti, Kennedy, Lisa M., Chavez, Violeta, Tan, Man-Wah, Lieb, Jason D., Grishok, Alla
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:en_US
Published: Public Library of Science 2012
Online Access:http://hdl.handle.net/1721.1/69091

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